NMR chemistry of red blood cell constituents.
نویسنده
چکیده
منابع مشابه
NMR chemistry analysis of red blood cell constituents in normal subjects and lithium-treated psychiatric patients.
Red blood cells from 18 lithium carbonate-treated patients with bipolar affective disorder and 12 normal volunteers were analyzed using 1H-nuclear magnetic resonance (NMR) spectroscopy. The spectra were analyzed for alanine, adenosine triphosphate (ATP), choline, 2,3-diphosphoglycerol, glucose, glutathione, glycine, and lactate. Significant elevations of choline and lactate were found in the li...
متن کاملOnly solid red blood cell ghosts transport K+, and Na+ against concentration gradients: hollow intact ghosts with K+-Na+ activated ATPase do not.
Human red blood cell ghosts, prepared by simple hypotonic lysis are filled with cytoplasmic proteins. These solid ghosts can transport K+ and Na+ against concentration gradients in the presence of ATP. In hollow red cell ghosts prepared by repeated hypotonic lysis followed by high salt wash, this ability to transport K+ and Na+ in the presence of ATP is lost even though these hollow ghost membr...
متن کاملQuantitative relationships between the concentration of proteins and the concentration of K+ and Na+ in red cell ghosts.
The concentration of K+ accumulated in and Na+ extruded from red blood cell ghosts are quantitatively correlated with the total protein contents of the ghosts with a linear correlation coefficient of +0.80. The straight line derived from the 43 sets of data on K+ accumulated in the presence of varying ghost proteins, when extrapolated to the protein content of a normal red blood cell, yields a ...
متن کاملExplaining on request a correlation between membrane Na,K-ATPase and K+ content in erythrocytes and other findings in the preceding paper.
In response to the request of the authors of the preceding paper, this article explains three observations they and others had made in the context of the association-induction hypothesis. (1) Why is Rb+ accumulated in human red blood cells not released when transferred to a Rb(+)-free Hank's solution? (2) Why ouabain, which reduces Rb+ uptake by red blood cells, does not release this ion from R...
متن کاملThe determination of the free magnesium level in the human red blood cell by 31P NMR.
The phosphorus NMR spectra of intracellular ATP in glycolyzing human red blood cells maintained at 37 degrees C in an atmosphere containing 5% CO2 have been obtained and quantitated under completely aerobic and anaerobic conditions. A comparison of the separation between the alphaP and betaP resonances and the alpha-beta and beta-gamma 31P spin-spin coupling constants of intracellular ATP with ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Biological psychiatry
دوره 22 3 شماره
صفحات -
تاریخ انتشار 1987